Sunday, July 24, 2016

Acne vulgaris

Common age: adolescent age 12-25 years.
But it can affect newborns and old aged patients. 
Cause: hormone imbalance is the main cause for development of acne
Types:
1] comedones : white heads or black heads
(mild variety)
2] papulopustular acne are of moderate variety
3] nodulocystic acne is severe form of acne
4] acne fulminans and
5]pyoderma faciale 
last two forms of acne which require aggressive treatment.

How is this treated?


1] Topical treatments: 
Tretinoin 0.025% cream at bedtime is effective in most of patients.
Others: adapalene gel 0.1%, brevoxyl cream, niacinamide gel, clindamycin cream, glycolic acid cream
These creams are useful for mild to moderate acne.
2] systemic/ oral treatments:
Tab azithromycin 500mg once a day for 3 days in a week for 1-3 months
Tab doxycycline 100 mg once daily for 1-3 months.
Tab minocycline 50mg once daily 
Tab isotretinoin 0.5-1 mg/kg once daily for 1-6 months
(Isotretinoin treatment is very effective in reducing acne eruption but careful monitoring of liver function and lipid profile is advised). One more important note: Isotretinoin is contraindicated in pregnancy.
Nodulocystic acne can be treated with intralesional triamcinolone acetonide 10 mg/ml.
Treatment of acne fulminans:
Systemic steroids at the beginning to control inflammation and then start antibiotics or isotretinoin. 

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